Breakdown of aberrant protein in rabbit reticulocytes decreases with cell age.
نویسندگان
چکیده
Rabbit reticulocytes, separated into ten cell age groups by bovine serum albumin density-gradient sedimentation, were pulse-labelled with [14C]leucine in the presence of either puromycin dihydrochloride or aminoethyl-L-cysteine (a lysine analogue). Intracellular proteolysis of both the puromyucinyl-peptides and analogue-containing protein decreased with cell maturity.
منابع مشابه
ATP serves two distinct roles in protein degradation in reticulocytes, one requiring and one independent of ubiquitin
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ورودعنوان ژورنال:
- The Biochemical journal
دوره 188 1 شماره
صفحات -
تاریخ انتشار 1980